1. Drew Brees vs. St. Louis Rams

Very few teams in the NFL can scheme to take away Drew Brees’s effectiveness. And St. Louis isn’t one of them. This game will be a laugher and Brees will throw for over 300 yards with at least three TDs against the over-matched Rams secondary. He’s our top fantasy football QB in Week Ten.

2. Kurt Warner vs. Seattle Seahawks

Warner’s coming off a five TD performance in a game that Pro Bowl receiver Anquan Boldin didn’t even play. He should be back for this one. The Seahawks, hurt by multiple injuries to key positions on their defense, will have no answer for Arizona’s passing game. We expect Warner to top 300-yards with three TDs.

3. Tom Brady vs. New England Patriots

In what should be a classic match-up on Sunday Night, expect Brady to get the better of Manning due to the recent losses (S Sanders, CB Jackson) to the Colts defense.  Brady will start out using the short passing game (RBs, Wes Welker, etc.) before taking his shots to a streaking Randy Moss down the sidelines.

4. Donovan McNabb vs. San Diego Chargers

McNabb’s coming off a poor performance in which he threw two ill advised interceptions in their Week Nine loss to the Cowboys. Things will improve Sunday. Look for a more consistent passing attack and for McNabb to test Cromartie and Jammer deep with their speedy receivers.

Sleepers

1. Mark Sanchez vs. Jacksonville Jaguars

The Jaguars pass rush is almost non-existent and Sanchez should have plenty of opportunities to locate Edwards, Keller and Cotchery for some big plays down the field. He’s an excellent fantasy sleeper and will top 225 yards with two scores.

2. Matt Cassel vs. Oakland Raiders

The lack of a Raiders pass rush makes Cassel an attractive sleeper option here. He’ll have an opportunity to spread it around and should toss at least two TDs in Oakland on Sunday.

Others We Like

Ben Roethlisberger vs. Cincinnati Bengals

The last time these two teams met, in what was a last second loss to the Bengals, Roethlisberger had ample opportunities to make big plays but the team failed to capitalize on them (see Limas Sweed TD drop in end zone). Look for a better result this time when Cincy comes to town.

Aaron Rodgers vs. Dallas Cowboys

Regardless of the poor protection up front, Rodgers, because of the skill players surrounding him, is still good enough to have solid fantasy numbers week in and week out.  Look for Jennings and Driver to get the better of Newman and Jenkins and for Rodgers to finish with another 250-yard game and multiple TDs.

Peyton Manning vs. New England Patriots

The Colts have become so one dimensional that Manning is enjoying one of his finest seasons to date. But defenses are beginning to catch up to the Colts offense and this has led to a slight drop off in production the past two weeks. Look for more of a balanced attack on Sunday but for Manning to still surpass 250 yards with a few scores.

A Few More

Carson Palmer vs. Pittsburgh Steelers

Jay Cutler vs. San Francisco 49ers

Joe Flacco vs. Cleveland Browns

Tony Romo vs. Green Bay Packers

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